Henderson-HasselbalchChemistry

Henderson-Hasselbalch Buffer pH & Capacity Calculator

Calculate buffer solution pH, conjugate base-to-acid ratio, and Van Slyke buffer capacity (β) from weak acid pKa and component molar concentrations.

Calculated Result

Buffer Solution pH

5.76pH

Calculator Inputs

-
Quick select:
M
Quick select:
M
Quick select:

Buffer Solution pH

5.76pH

Conjugate Base to Acid Ratio

1.5 -

Buffer Capacity (β)

0.14 M/pH unit

Buffer System Indicators

pKa Value
4.76 -(45%)
Buffer pH
5.76 pH(55%)

Standard biochemistry and analytical chemistry tool for buffer preparation and physiological equilibrium.

Calculation Methodology

Henderson-Hasselbalch Equation: pH = pKa + log10( [Conjugate Base A-] / [Weak Acid HA] ). Optimal buffering occurs when [A-] = [HA], where pH = pKa.

Frequently Asked Questions

The accepted buffering range is typically pH = pKa ± 1. Outside this interval, one component is depleted, causing resistance to pH changes to drop dramatically.

Related Calculators

Recommended tools and calculators tailored to your current calculation

Explore all tools